Recombinant Anti-human Aβ42 Intrabody [Tat]
Recombinant anti-Aβ42 intrabody in fusion with HIV Tat works within cells and is directed against intracellur Aβ42, expressed in E. coli cells. The intrabodies, one with an endoplasmic reticulum (ER) targeting signal and one devoid of a targeting sequence, were assessed in cells harboring a doxycycline (Dox)-regulated mutant human amyloid precursor protein Swedish mutant (hAPPswe) transcription unit for their abilities to prevent Aβ peptide egress.
| Supplier | Creative Biolabs |
|---|---|
| Product # | IAB-B042(T) |
| Pricing | Inquiry |
| Host | human |
| Target | Aβ42 |
| Species Reactivity | human |
| Type | scFv-Tat |
| Applications | Can be useful in applications such as: Enzyme-linked Immunosorbent Assay; Neutralization; Functional studies |
| Storage | Store at – 20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles. |