Navitoclax (ABT-263)
Navitoclax (ABT-263) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤1 nM in cell-free assays, but binds more weakly to Mcl-1 and A1. Phase 2.
Supplier | Selleck Chemicals |
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Product # | S1001 |
Sku # | S1001-10mM/1mL |
Pricing | 10mM/1mL, $97.00 |
Citations for this product:
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bioRxiv - Cancer Biology 2020Quote: ... navitoclax (Selleck Chemicals # S1001), fulvestrant (Sigma Aldrich # I4409) ...
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bioRxiv - Cell Biology 2024Quote: ... cells were treated with the senolytic ABT263/Navitoclax (Selleck Chemicals, S1001) at different concentrations for 24 h ...
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bioRxiv - Cancer Biology 2023Quote: Drug concentrations used in this study are as follows: navitoclax (10uM Selleck Chemicals #S1001), fisetin (10uM ...