Gefitinib hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-50895A-500 mg |
| CAS # | 184475-55-6 |
| Pricing | 500 mg, USD $72.0 |
| Synonyms | ZD-1839 hydrochloride |
| MWt | 483.36 |
| Formula | C₂₂H₂₅Cl₂FN₄O₃ |
| Biological Activity | Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib hydrochloride selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy. Gefitinib hydrochloride has antitumour activity[1][2]. |
| Purity | 99.85% |