CDDO-dhTFEA
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-112671-100 mg |
| CAS # | 1191265-33-4 |
| Pricing | 100 mg, USD $1650.0 |
| Synonyms | RTA dh404 |
| MWt | 574.72 |
| Formula | C₃₃H₄₅F₃N₂O₃ |
| Biological Activity | CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB[1]. CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats[2]. |
| Purity | 99.71% |