| Supplier |
Creative Peptides |
| Product # |
P75018 |
| Pricing |
Inquire
|
| MolecularWeight |
1698
|
| Sequence |
- One Letter Code: MASGVMVSDDVVKVFN
- Three Letter Code: H-Met-Ala-Ser-Gly-Val-Met-Val-Ser-Asp-Asp-Val-Val-Lys-Val-Phe-Asn-OH
|
| Storage |
-20°C
|
| Explanation |
This peptide contains the unique amino-terminal phosphorylation site of Xenopus ADF/cofilin, the LIM kinase (LIMK) phosphorylation site. LIMK1 is a key regulator of the actin cytoskeleton through its phosphorylation of ADF/cofilin at serine-3 for inactivation. This peptide is a fragment of the S3 peptide containing the serine-3 sequence of ADF/cofilin that has been widely used as an effective competitive inhibitor of LIMK1.
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| Reference |
Wen, Z. et al. J. Cell Biol. 178, 107 (2007).
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