Tat-NR2B9c

Supplier MedChemExpress
Product # HY-P0117-5 mg
CAS # 500992-11-0
Pricing 5 mg, USD $216.0
Biological Activity Tat-NR2B9c (Tat-NR2Bct; NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy[1][2][5].
Synonyms Tat-NR2Bct; NA-1
MWt 2518.88
Formula C₁₀₅H₁₈₈N₄₂O₃₀
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