Human Anti-TGFBR2 Recombinant Antibody (clone TGF1)
Provided are novel isolated anti-TGFPRII mAbs. The antibody are capable of the following activities: displaying high affinity binding toward the extracellular domain of human TGFPRII; blocking the binding of TGORII ligands (TGF131, TGO2, and TGO3) to TGFf3RII, thereby inhibiting TGFf3-induced Smad2 phosphorylation; internalizing TGORII, which can act as a signaling down-regulation mechanism independent of ligand-receptor interaction; inhibiting ligand-induced TGORII signaling pathways and inhibiting TGORII-mediated cellular activities.
| Supplier | Creative Biolabs |
|---|---|
| Product # | HPAB-0232-YC |
| Pricing | Inquiry |
| Host | Human |
| Target | TGFBR2 |
| Species Reactivity | Human |
| Type | Humanized IgG |
| Applications | ELISA, FuncS |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |