Recombinant Human Karyopherin Alpha 2 (RAG cohort 1, importin alpha 1), His-tagged

Karyopherinalpha2 (KPNA2) is a member of the karyopherin alpha family. This proteinplays a key role in the nuclear import of proteins with a classical nuclearlocalization signal (NLS). KPNA2 bound in vitro specifically and directly tosubstrates containing either a simple or bipartite NLS motif. It promoteddocking of import substrates to the nuclear envelope and together withrecombinant human Ran reconstituted complete nuclear protein import.

• Supplier: Creative Biomart
• Product #: KPNA2-1389H