Substance P (1-7)

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Product # R1875
CAS # 68060-49-1
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MolecularFormula C41H65N13O10
MolecularWeight 900
Sequence
  • One Letter Code: RPKPQQF
  • Three Letter Code: Arg-Pro-Lys-Pro-Gln-Gln-Phe
Storage -20°C
ShippingCondition Evaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
Explanation Substance P (SP) is an endogenous tachykinin neuropeptide that is involved in inflammatory, pain, and stress signaling; it exhibits neuroprotective, cognition-enhancing, and gastrointestinal motility modulating activities. SP is the natural ligand for the neurokinin-1 (NK1) receptor.
ChemicalName 2-[[5-amino-2-[[5-amino-2-[[1-[6-amino-2-[[1-[2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoic acid
InChI InChI=1S/C41H65N13O10/c42-19-5-4-12-28(51-37(60)30-13-7-21-53(30)38(61)25(43)11-6-20-48-41(46)47)39(62)54-22-8-14-31(54)36(59)50-27(16-18-33(45)56)34(57)49-26(15-17-32(44)55)35(58)52-29(40(63)64)23-24-9-2-1-3-10-24/h1-3,9-10,25-31H,4-8,11-23,42-43H2,(H2,44,55)(H2,45,56)(H,49,57)(H,50,59)(H,51,60)(H,52,58)(H,63,64)(H4,46,47,48)
InChIKey KPHDBQWTCKBKIL-UHFFFAOYSA-N
CanonicalSMILES C1CC(N(C1)C(=O)C(CCCN=C(N)N)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)O
Solubility 10 mM in H2O
Purity ≥97% (HPLC)
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