Smac/DIABLO Antibody
Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/caspase-9 pathway. Smac/DIABLO binds to IAPs (Inhibitor of Apoptosis Proteins) and neutralizes the inhibitory effect of IAPs. Analysis of the structural basis of Smac/DIABLO has revealed that the N-terminal amino acids are required for Smac/DIABLO to bind to IAPs and activation of caspases.
| Supplier | Creative Biogene |
|---|---|
| Product # | PBCA1025 |
| Pricing | Inquiry |
| Isotype | Rabbit IgG |
| Research Area | Antibody |
| Antibody Target | Smac/DIABLO |
| Antibody Type | Polyclonal |
| Application | WB, IHC |
| Formulation | 0.5 mg/ml of antibody in PBS, pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin |
| Appearance | Liquid |
| Host | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Usage Statement | Our products are intended for research use only and are not to be used for other purposes, including but are not limited to in vitro diagnostic uses, ex vivo or in vivo therapeutic uses. |