Anti-Human EGFR Therapeutic Antibody (Zalutumumab)
Recombinant monoclonal antibody to EGFR. Zalutumumab (proposed trade name HuMax-EGFr) is a fully human IgG1 monoclonal antibody (mAb) directed towards the epidermal growth factor receptor (EGFr). the Netherlands. Specifically, zalutumumab is designed for the treatment of squamous cell carcinoma of the head and neck (SCCHN), a type of cancer. The current treatment for SCCHN includes tyrosine kinase inhibitors and human monoclonal antibodiess. In addition, murine mAbs were tested successfully in mice, but caused an immune response in humans and were thus determined as ineffective in therapeutics.
| Supplier | Creative Biolabs |
|---|---|
| Product # | TAB-040 |
| Pricing | Inquiry |
| Host | Human |
| Target | EGFR |
| Species Reactivity | Human |
| Type | IgG1 - kappa |
| Applications | ELISA, FC, IP, FuncS, IF, Neut, ICC |
| Storage | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |