| Supplier |
Creative Peptides |
| Product # |
10-101-305 |
| CAS # |
13433-09-5 |
| Pricing |
Inquire
|
| MolecularFormula |
C13H16N2O5
|
| MolecularWeight |
280.28
|
| Sequence |
- One Letter Code: DF
- Three Letter Code: L-Asp-L-phe
|
| ShippingCondition |
+20°C (International: -20°C)
|
| Explanation |
L-Aspartyl-L-phenylalanine is a dipeptide inhibitor of angiotensin-converting enzyme (ACE) and a metabolite of the synthetic non-caloric sweetener aspartame. It is formed from aspartame by intestinal intracellular esterases. L-Aspartyl-L-phenylalanine inhibits ACE with a Ki value of 11 µM for the rabbit enzyme. Serum levels of L-aspartyl-L-phenylalanine are positively associated with pancreatic ductal adenocarcinoma.
|
| ChemicalName |
(3S)-3-amino-4-[[(1S)-1-carboxy-2-phenylethyl]amino]-4-oxobutanoic acid
|
| Activity |
Inhibitor
|
| InChI |
InChI=1S/C13H16N2O5/c14-9(7-11(16)17)12(18)15-10(13(19)20)6-8-4-2-1-3-5-8/h1-5,9-10H,6-7,14H2,(H,15,18)(H,16,17)(H,19,20)/t9-,10-/m0/s1
|
| InChIKey |
YZQCXOFQZKCETR-UWVGGRQHSA-N
|
| CanonicalSMILES |
C1=CC=C(C=C1)CC(C(=O)O)NC(=O)C(CC(=O)O)N
|
| IsomericSMILES |
C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)O)N
|
| Target |
Angiotensin-converting Enzyme (ACE)
|
| Purity |
>98 %
|