BRD4770
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-16705-10 mM * 1 mL |
| CAS # | 1374601-40-7 |
| Pricing | 10 mM * 1 mL, USD $99.0 |
| Biological Activity | BRD4770 is a histone methyltransferase G9a inhibitor. BRD4770 reduces di- and trimethylation of lysine 9 on histone H3 (H3K9) with an EC50 of 5 µM, and has less or little effect toward H3K27me3, H3K36me3, H3K4me3, and H3K79me3. BRD4770 can activate the ataxia telangiectasia mutated (ATM) pathway and induce cell senescence[1]. |
| Purity | 99.77% |
| MWt | 413.47 |
| Formula | C₂₅H₂₃N₃O₃ |