BI-3406
Supplier | MedChemExpress |
---|---|
Product # | HY-125817-10 mg |
CAS # | 2230836-55-0 |
Pricing | 10 mg, USD $650.0 |
Biological Activity | BI-3406 (compound I-6) is an orally active, highly potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with an IC50 of 6 nM. BI-3406 potently reduces the formation of GTP-loaded KRAS, and inhibits MAPK pathway signaling. BI-3406 has anticancer activity[1][2]. |
Purity | 99.79% |
MWt | 462.46 |
Formula | C₂₃H₂₅F₃N₄O₃ |