(Z)-SMI-4a
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-16576A |
| CAS # | 438190-29-5 |
| Pricing | inquire |
| Biological Activity | (Z)-SMI-4a is a poten, selective, cell-permeable and ATP-competitive Pim-1 inhibitor with an IC50 of 24 μM and a Ki of 0.6 µM. (Z)-SMI-4a also inhibits Pim-2 (IC50 of 100 μM), and does not significantly inhibit the other serine/threonine- or tyrosine-kinases. (Z)-SMI-4a has anticancer activity[1]. |
| MWt | 273.23 |
| Formula | C₁₁H₆F₃NO₂S |