Merestinib dihydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15514A-50 mg |
| CAS # | 1206801-37-7 |
| Pricing | 50 mg, USD $540.0 |
| Synonyms | LY2801653 dihydrochloride |
| MWt | 625.45 |
| Formula | C₃₀H₂₄Cl₂F₂N₆O₃ |
| Biological Activity | Merestinib dihydrochloride (LY2801653 dihydrochloride) is a potent, orally bioavailable c-Met inhibitor (Ki=2 nM) with anti-tumor activities. Merestinib dihydrochloride also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK (IC50=10 nM), TEK (IC50=63 nM), ROS1, DDR1/2 (IC50=0.1/7 nM) and MKNK1/2 (IC50=7 nM)[1][2]. |
| Purity | 99.36% |