(Des-Glu22)-Amyloid β-Protein (1-40)
Osaka mutation is the first deletion type mutation found in APP and Aβ. Aβ E22delta mutant is more resistant to degradation of two major Aβ-degrading enzymes, neprilysin and insulin-degrading enzyme. The synthetic mutant Aβ has unusual aggregation properties, with enhanced oligomerization but no fibrillization. It inhibits long-term hippocampal enhancement more effectively than wild-type Aβ.
| Supplier | BOC Sciences |
|---|---|
| Product # | BAT-014675 |
| Pricing | Inquire |
| Cas | 1678416-36-8 |
| Molecular Weight | 4200.75 |
| Molecular Formula | C189H288N52O55S |