PF-5274857

Supplier MedChemExpress
Product # HY-13459-50 mg
CAS # 1373615-35-0
Pricing 50 mg, USD $450.0
Biological Activity PF-5274857 is a potent, selective, orally active and brain-penetrant antagonist of Smo, with an IC50 of 5.8 nM and Ki of 4.6 nM. PF-5274857 has potential for research of tumor types including brain tumors and brain metastasis driven by an activated Hh pathway[1].
Purity 98.12%
MWt 436.96
Formula C₂₀H₂₅ClN₄O₃S
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