WDR5-IN-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-133121 |
| CAS # | 2408842-51-1 |
| Pricing | inquire |
| Biological Activity | WDR5-IN-1 is a potent and selective WD repeat domain 5 (WDR5) inhibitor, with a Kd of <0.02 nM. WDR5-IN-1 inhibits MLL1 histone methyltransferase (HMT) activity with an IC50 of 2.2 nM. WDR5-IN-1 diminishes MYC recruitment at WDR5-displaced genes and exhibits potent anti-proliferative effects in CHP-134 (neuroblastoma) and Ramos (Burkitt’s lymphoma) lines[1]. |
| MWt | 514.59 |
| Formula | C₃₀H₃₁FN₄O₃ |