Licofelone
Supplier | MedChemExpress |
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Product # | HY-B1452-10 mM * 1 mL |
CAS # | 156897-06-2 |
Pricing | 10 mM * 1 mL, USD $55.0 |
Synonyms | ML-3000 |
MWt | 379.88 |
Formula | C₂₃H₂₂ClNO₂ |
Biological Activity | Licofelone (ML-3000) is a dual COX/5-lipoxygenase (5-LOX) inhibitor (IC50=0.21/0.18 μM, respectively) for the treatment of osteoarthritis. Licofelone exerts anti-inflammatory and anti-proliferative effects. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins[1][2][3]. |
Purity | ≥99.0% |