PHA-767491 HCl
PHA-767491 (CAY10572, NMS 1116354) HCl is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM in cell-free assays, respectively.It displays ~20-fold selectivity against CDK1/2 and GSK3-β, 50-fold selectivity against MK2 and CDK5, 100-fold selectivity against PLK1 and CHK2.
Supplier | Selleck Chemicals |
---|---|
Product # | S2742 |
Sku # | S2742-10mM/1mL |
Pricing | 10mM/1mL, $120.00 |