Sirtuin 2, human recombinant
Human sirtuins function as intracellular regulatory proteins. Sirtuin 2 is a member of the class III histone deacetylases (HDACs) and has been implicated in many cellular processes that include histone deacetylation, gene silencing, chromosomal stability, and aging. The enzymatic activity of class III HDACs is nicotinamide adenine dinucleotide (0.1mM NAD+) dependent and insensitive to HDAC inhibitor trichostatin A.
| Supplier | CD BioSciences |
|---|---|
| Product # | APE-054 |
| Pricing | , Inquire |
| Product Category | Proteins/Enzymes |
| Gene ID | 22933 |
| Alternate Name | NAD-dependent protein deacetylase sirtuin-2, Regulatory protein SIR2 homolog 2, SIR2-like protein 2 |
| Molecular Weight | 43 kDa |
| Appearance | Liquid |
| Storage Conditions | -80°C |
| Gene Symbol | SIRT2 |
| Source | E. coli |
| Physical Form Description | rh-Sirtuin 2 (SIRT2) with the native N-terminus is supplied as a liquid of 2 mg/ml in 25 mM Tris, pH 7.5, 100 mM NaCl, 2.7 mM KCl, 3 mM MgCl2, 10 % glycerol. |
| Purity by SDS-PAGE | ≥90% |