Olodanrigan (EMA401)
Olodanrigan (EMA401, PD-126055, (S) PD-126055) is a highly selective, orally active, peripherally restricted antagonist of angiotensin II type 2 receptor (AT2R). Olodanrigan (EMA401) analgesic action appears to involve the inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons.
Supplier | Selleck Chemicals |
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Product # | S0326 |
Sku # | S0326-5mg |
Pricing | 5mg, $427.00 |