Fedratinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10409-200 mg |
| CAS # | 936091-26-8 |
| Pricing | 200 mg, USD $250.0 |
| Synonyms | TG-101348; SAR 302503 |
| MWt | 524.68 |
| Formula | C₂₇H₃₆N₆O₃S |
| Biological Activity | Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research[1][2]. |
| Purity | ≥98.0% |