R-8507
R-8507 is an antagonist of the TNF-α type 1 receptor (TNF-αRI). It inhibits the expression of intercellular adhesion molecule-1 (ICAM-1) induced by TNF-α and IL-1β in an ELISA using A549 lung epithelial cells.
| Supplier | BOC Sciences |
|---|---|
| Product # | 338773-13-0 |
| Pricing | Inquire |
| Cas | 338773-13-0 |
| Molecular Weight | 348.7 |
| Molecular Formula | C16H8ClF3N4 |
| Canonical SMILES | C1=CC=C2C(=C1)N=C(C3=NN=C(N23)C4=CC=C(C=C4)Cl)C(F)(F)F |