RXDX-106 (CEP-40783)
RXDX-106 (CEP-40783) is an orally-available, potent and selective TAM(TYRO3, AXL, MER)/Met (c-Met) inhibitor displaying low nanomolar biochemical activity and slow (T1/2 >120 min) inhibitor off-rate in peptide phosphorylation assays and in vitro kinase binding assays, respectively.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S8570 |
| Sku # | S8570-5mg |
| Pricing | 5mg, $170.00 |
Citations for this product:
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bioRxiv - Immunology 2020Quote: ... exECs were treated with 25 µM RXDX-106 (CEP-40783, s8570, Selleck Chemicals) 30 minutes prior to incubation with dexamethasone treated or z-VAD-FMK treated thymocytes ...