NKL 22
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-100384-10 mM * 1 mL |
| CAS # | 537034-15-4 |
| Pricing | 10 mM * 1 mL, USD $66.0 |
| Biological Activity | NKL 22 (compound 4b) is a potent and selective inhibitor of histone deacetylases (HDAC), with an IC50 of 199 and 69 nM for HDAC1 and HDAC3, respectively. NKL 22 exhibits selectivity over HDAC2/4/5/7/8 (IC50≥1.59 μM). NKL 22 ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice[1][2][3]. |
| MWt | 325.4 |
| Formula | C₁₉H₂₃N₃O₂ |