Recombinant Human CD48 Protein, Fc-tagged, FITC conjugated

CD48, also known as SLAMF2, BCM-1 and BLAST-1, is a 65 kDa GPIlinked protein belonging to the CD2 subfamily of immunoglobulinsuperfamily molecules. In rodents, CD48 is the ligand for CD2 whereas in humans, CD58 is the ligand for CD2. Human CD48 cDNA encodes a 243 aa precursor that includes a 26 aa signal sequence, a 194 aa mature protein that contains one Ig-like V-type domain and one Ig-like C2-type domain, and a 23 aa C-terminal propeptide. It has a high degree of sequence homology to CD58 (LFA-3), and human CD48 shares approximately 50% aa sequence identity with mouse and rat CD48. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.

• Supplier: Creative Biomart
• Product #: CD48-252HF
• Product Category: Recombinant Protein
• Shipping Country: USA