Entrectinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12678-5 mg |
| CAS # | 1108743-60-7 |
| Pricing | 5 mg, USD $60.0 |
| Synonyms | NMS-E628; RXDX-101 |
| MWt | 560.64 |
| Formula | C₃₁H₃₄F₂N₆O₂ |
| Biological Activity | Entrectinib (NMS-E628) is a potent, orally available, and CNS-active pan-Trk, ROS1, and ALK inhibitor. Entrectinib inhibits TrkA, TrkB, TrkC, ROS1 and ALK with IC50 values of 1, 3, 5, 12 and 7 nM, respectively. Antitumor activity. |
| Purity | 99.32% |