COH34
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-128760-100 mg |
| CAS # | 906439-72-3 |
| Pricing | 100 mg, USD $2250.0 |
| Biological Activity | COH34 is a potent and specific poly(ADP-ribose) glycohydrolase (PARG) inhibitor with an IC50 of 0.37 nM. COH34 binds to the catalytic domain of PARG (Kd=0.547 μM), thereby prolonging PARylation at DNA lesions and trapping DNA repair factors[1]. |
| Purity | ≥98.0% |
| MWt | 293.38 |
| Formula | C₁₈H₁₅NOS |