Zamicastat
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-106004-10 mg |
| CAS # | 1080028-80-3 |
| Pricing | 10 mg, USD $450.0 |
| Synonyms | BIA 5-1058 |
| MWt | 401.47 |
| Formula | C₂₁H₂₁F₂N₃OS |
| Biological Activity | Zamicastat (BIA 5-1058) is a dopamine β-hydroxylase (DBH) inhibitor and can cross the blood-brain barrier (BBB) to cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC50 values of 73.8 μM and 17.0 μM, respectively[1]. Zamicastat reduces high blood pressure[2]. |
| Purity | ≥98.0% |