Aminopterin
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-14518-10 mg |
| CAS # | 54-62-6 |
| Pricing | 10 mg, USD $100.0 |
| Biological Activity | Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia[1][2]. |
| Synonyms | 4-Aminofolic acid; APGA |
| MWt | 440.41 |
| Formula | C₁₉H₂₀N₈O₅ |