SPR inhibitor 3
Supplier | MedChemExpress |
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Product # | HY-115510-10 mg |
CAS # | 1292285-54-1 |
Pricing | 10 mg, USD $185.0 |
Synonyms | SPRi3 |
MWt | 262.3 |
Formula | C₁₄H₁₈N₂O₃ |
Biological Activity | SPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 μM). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels[1][2][3]. |
Purity | 99.91% |