187-1, N-WASP inhibitor
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-P1045 |
| CAS # | 380488-27-7 |
| Pricing | inquire |
| Biological Activity | 187-1, N-WASP inhibitor, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC50 of 2 μM. 187-1, N-WASP inhibitor prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein[1][2]. |
| MWt | 1784.11 |
| Formula | C₉₆H₁₂₂N₁₈O₁₆ |