Talmapimod hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10406A |
| CAS # | 309915-12-6 |
| Pricing | inquire |
| Biological Activity | Talmapimod (SCIO-469) hydrochloride is an orally active, selective, and ATP-competitive p38α inhibitor with an IC50 of 9 nM. Talmapimod hydrochloride shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs[1][2][3]. |
| Synonyms | SCIO-469 hydrochloride |
| MWt | 549.46 |
| Formula | C₂₇H₃₁Cl₂FN₄O₃ |