Alvimopan dihydrate

Supplier MedChemExpress
Product # HY-76657A-10 mg
CAS # 170098-38-1
Pricing 10 mg, USD $160.0
Synonyms ADL 8-2698 dihydrate; LY 246736 dihydrate
MWt 460.56
Formula C₂₅H₃₆N₂O₆
Biological Activity Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC50 of 1.7 nM. Alvimopan dihydrate has selectivity for μ-opioid receptor (Ki=0.47 nM) over κ- and δ-opioid receptors (Kis=100, 12 nM, respectively). Alvimopan dihydrate can be used for the research of postoperative ileus[1][2][3].
Purity 98.70%
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