SIRT7 inhibitor 97491

Supplier MedChemExpress
Product # HY-135899-10 mM * 1 mL
CAS # 1807758-81-1
Pricing 10 mM * 1 mL, USD $440.0
Biological Activity SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.[1].
Purity 98.05%
MWt 285.73
Formula C₁₅H₁₂ClN₃O
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