Vimirogant hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-103637A-5 mg |
| Pricing | 5 mg, USD $1750.0 |
| Biological Activity | Vimirogant (VTP-43742) hydrochloride is a potent, selective, and orally active RORγt inhibitor (Ki=3.5 nM; IC50=17 nM). Vimirogant hydrochloride exhibits >1000-fold selectivity versus the RORα and RORβ isotypes. Vimirogant hydrochloride inhibits Th17 differentiation and IL-17A secretion from mouse splenocytes (IC50=57 nM) without affecting Th1, Th2, or Treg cell differentiation. Vimirogant hydrochloride has the potential for autoimmune disorders research[1][2]. |
| Purity | 98.33% |
| Synonyms | VTP-43742 hydrochloride |
| Formula | C₂₇H₃₅F₃N₄O₃S.xHCl |