Alectinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13011-10 mM * 1 mL |
| CAS # | 1256580-46-7 |
| Pricing | 10 mM * 1 mL, USD $79.0 |
| Synonyms | CH5424802; RO5424802; AF802 |
| MWt | 482.62 |
| Formula | C₃₀H₃₄N₄O₂ |
| Biological Activity | Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively[1]. Alectinib demonstrates effective central nervous system (CNS) penetration[2]. |
| Purity | 99.87% |