FzM1.8
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-117163-10 mg |
| CAS # | 2204290-85-5 |
| Pricing | 10 mg, USD $170.0 |
| Biological Activity | FzM1.8 derives from FzM1, is an allosteric agonist of FZD4 with pEC50 of 6.4. FzM1.8 binds to FZD4 and activates the WNT/β-catenin pathway, by promoting TCF/LEF transcriptional activity in the absence of any WNT ligand. FzM1.8 binding stabilizes FZD4 with an increased affinity for heterotrimeric G protein and stimulates the release of the Gβγ subunit that in turn activates PI3K[1]. |
| Purity | 98.20% |
| MWt | 322.31 |
| Formula | C₁₈H₁₄N₂O₄ |