| Supplier |
MedChemExpress |
| Product # |
HY-14374-5 mg (11.38 mM * 1 mL in Methanol) |
| CAS # |
1202580-59-3 |
| Pricing |
5 mg (11.38 mM * 1 mL in Methanol), USD $540.0
|
| Synonyms |
CAY10618
|
| MWt |
439.55
|
| Formula |
C₂₇H₂₉N₅O
|
| Biological Activity |
GPP78 (CAY10618) is a potent Nampt inhibitor with an IC50 of 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion. GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells with an IC50 of 3.8 nM by inducing autophagy. GPP78 has anti-cancer and anti-inflammatory effects[1][2].
|
| Purity |
≥99.0%
|