Senicapoc
Supplier | MedChemExpress |
---|---|
Product # | HY-50694-10 mg |
CAS # | 289656-45-7 |
Pricing | 10 mg, USD $108.0 |
Synonyms | ICA-17043 |
MWt | 323.34 |
Formula | C₂₀H₁₅F₂NO |
Biological Activity | Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca2+-activated K+ channel; KCa3.1) blocker with an IC50 of 11 nM. Senicapoc blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM[1]. |
Purity | 99.73% |