Indomethacin-D4
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-14397S |
| CAS # | 87377-08-0 |
| Pricing | inquire |
| Biological Activity | Indomethacin-D4 (Indometacin-D4) is a deuterium labeled Indomethacin. Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells[1]. Indomethacin disrupts autophagic flux by disturbing the normal functioning of lysosomes[2]. |
| Synonyms | Indometacin-D4 |
| MWt | 361.81 |
| Formula | C₁₉H₁₂D₄ClNO₄ |