7-Ethyl-10-hydroxycamptothecin
SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively.
| Supplier | BOC Sciences |
|---|---|
| Product # | B0084-099455 |
| Pricing | 1 g/unit USD $199 |
| Cas | 86639-52-3 |
| Molecular Weight | 392.40 |
| Molecular Formula | C22H20N2O5 |
| Canonical SMILES | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)O |