AMG-47a
Supplier | MedChemExpress |
---|---|
Product # | HY-18303-5 mg |
CAS # | 882663-88-9 |
Pricing | 5 mg, USD $180.0 |
Biological Activity | AMG-47a is a potent and orally active lymphocyte-specific protein tyrosine kinase (Lck) inhibitor, with an IC50 of 0.2 nM. AMG-47a also inhibits VEGF2, p38α, Jak3 and MLR and IL-2 with IC50s of 1 nM, 3 nM, 72 nM, 30 nM and 21 nM, respectively. AMG-47a has anti-inflammatory activity[1]. |
Purity | 98.71% |
MWt | 535.56 |
Formula | C₂₉H₂₈F₃N₅O₂ |