AMG-47a

Supplier MedChemExpress
Product # HY-18303-5 mg
CAS # 882663-88-9
Pricing 5 mg, USD $180.0
Biological Activity AMG-47a is a potent and orally active lymphocyte-specific protein tyrosine kinase (Lck) inhibitor, with an IC50 of 0.2 nM. AMG-47a also inhibits VEGF2, p38α, Jak3 and MLR and IL-2 with IC50s of 1 nM, 3 nM, 72 nM, 30 nM and 21 nM, respectively. AMG-47a has anti-inflammatory activity[1].
Purity 98.71%
MWt 535.56
Formula C₂₉H₂₈F₃N₅O₂
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