Oximidine III
It is produced by the strain of Pseudomonas sp. QN05727. It's an anti-tumor antibiotic. It can selectively inhibit the growth of 3Y1 in rat fibroblasts with degeneration of various tumor genes. It inhibits v-H-ras-3Y1, v-src-3Y1 cells and the normal 3Y1 cells with IC50 (nmol/L) of 14, 4.5 and 140, respectively. It stops RAS-or SRC-denatured cells at G1 phase of the cell cycle and increases p21WAF1 expression.
| Supplier | BOC Sciences |
|---|---|
| Product # | BBF-02329 |
| Pricing | Inquire |
| Molecular Weight | 424.45 |
| Molecular Formula | C23H24N2O6 |
| Canonical SMILES | CON=CC=CC(=O)NC=CCC1CC2C(O2)C=CC=CC3=C(C(=CC=C3)O)C(=O)O1 |