Human Anti-HIV-1 gp120 Recombinant Antibody (clone F105); Fab Fragment
Recombinant Human Antibody (F105) Fab Fragment is specific to HIV-1 gp120, expressed in mammalian cells. F105 is a neutralizing, CD4–binding site (CD4BS) antibody, binding to gp120 occurred primarily through heavy-chain interactions, which were similar in many respects to those of CD4. F105 recognized conformational shifts in the position of the V1/V2 stem, resulting in a V1/V2 orientation poorly compatible with the functional viral spike.
Supplier | Creative Biolabs |
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Product # | PFBW-160 |
Pricing | Inquiry |
Host | Human |
Target | HIV-1 gp120 |
Species Reactivity | HIV-1 |
Type | Human Fab |
Applications | FC, Neut |
Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |