RU-SKI 43 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-18366A-50 mg |
| CAS # | 1782573-67-4 |
| Pricing | 50 mg, USD $828.0 |
| Biological Activity | RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. RU-SKI 43 hydrochloride reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. RU-SKI 43 hydrochloride has anti-cancer activity[1]. |
| Purity | 98.54% |
| MWt | 423.01 |
| Formula | C₂₂H₃₁ClN₂O₂S |