CKI-7 free base
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-133028-10 mM * 1 mL |
| CAS # | 120615-25-0 |
| Pricing | 10 mM * 1 mL, USD $157.0 |
| Biological Activity | CKI-7 free base is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 μM and a Ki of 8.5 μM. CKI-7 free base is a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 free base has a much weaker effect on casein kinase II and other protein kinases[1][2][3][4]. |
| Purity | 99.31% |
| MWt | 285.75 |
| Formula | C₁₁H₁₂ClN₃O₂S |