Pifithrin-α, p-Nitro, Cyclic
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-123076-50 mg |
| CAS # | 60477-38-5 |
| Pricing | 50 mg, USD $520.0 |
| Synonyms | PFN-α |
| MWt | 299.35 |
| Formula | C₁₅H₁₃N₃O₂S |
| Biological Activity | Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form p53 inhibitor. Pifithrin-α, p-Nitro, Cyclic is one order magnitude more active than Pifithrin-α in protecting cortical neurons exposed to Etoposide (ED50=30 nM). Pifithrin-α, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-α, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue[1][2]. |
| Purity | ≥99.0% |